- LaHood, Ray - United States Secretary of Transportation.
- Lamar, Lucius Q. C. (1825-1893) - Chairman of the United States Senate Committee on Railroads 1880-1881.
- Laney, David M. (born 1949) - Chairman of the Board of Directors for Amtrak 2002-present.
- Larson, Jim (1935-2008) - Telegrapher for Milwaukee Road; dispatcher and division manager for Chicago & North Western Railway; assistant vice president of operations for Amtrak -1998; worked to extend the Sunset Limited from New Orleans to Miami.
- Lewis, Roger (1912-1987) - First president of Amtrak 1971-1974. (Phillips, June 1991, p 27)
- Ledyard, Henry Brockholst (1844-1921) - Began his railroad career in 1870 workin in the Engineering Department of Northern Pacific Railroad. He left that job to become a clerk for the Chicago, Burlington & Quincy Railroad later in the same year. He worked through promotions to become Assistant Superintendent, and then Superintendent of the railroad's eastern division. He became the assistant to William B. Strong in 1874 who was then Superintendent of the Michigan Central Railroad. Ledyard replaced Strong in that position in 1876. He succeeded William H. Vanderbilt as president of the Michigan Central in 1883. Under Ledyard's leadership, the railroad removed a great number of bridges, tight curves and steep grades, increasing the maximum train length from 30 to 80 cars and doubling the car capacities at the same time. Ledyard then guided the construction of new lines along the Detroit River, which led to the construction of many large manufacturing plants, including the more well-known automobile plants of today. Ledyard stepped down from the presidency in 1905 but remained Chairman of the Board.
- Lemon, Ernest (1884-1954) - Chief mechanical engineer for London, Midland & Scottish Railway 1931-1932; later promoted to be vice president of same.
- Lenroot, Irvine L. (1869-1949) - Chairman of the United States Senate Committee on Railroads 1919-1921.
- List, Friedrich (1789-1846) - German economist who strongly advocated for a national railway system in Germany as a means of economic unification within the country.
- Lindholt, Tore (born 1941) - Director general of Norges Statsbaner 1987-1988; president of Norges Statsbaner 1990.
- Locke, Joseph (1805-1860) - English civil engineer; construction engineer of Stockton & Darlington Railway and Liverpool & Manchester Railway; Chief Mechanical Engineer for Grand Junction Railway.
- Loewy, Raymond (1893-1986) - Industrial designer who worked for Pennsylvania Railroad; his most prominent designs for PRR included the S1 and T1 locomotives.
- Lord, Henry C. (1824-1884) - President of Atchison, Topeka & Santa Fe Railway 1868-1869.
- Loree, Leonor F. (1858-1940) - President of Baltimore & Ohio Railroad 1901-1904, Chicago, Rock Island & Pacific Railroad __-1904, Delaware & Hudson Railroad 1907-1938, Kansas City Southern Railway 1918-1920, and chairman of Missouri-Kansas-Texas Railroad 1926-1928.
- Loubser, Kobus - Chief mechanical engineer of South African Railways.
- Lovett, Robert S. (1860-1932) - Chairman of the Southern Pacific Company Executive Committee 1909-1913; President of Union Pacific Railroad 1910-1911.
- Luhrsen, J. G. - Executive Secretary of the Railway Labor Executives' Association. (Palmer 1942)
- Luna, Charles - President of the United Transportation Union.
- Lyster, J. W. "Wes" (1923-2009) - Vice president of Canadian Brotherhood of Locomotive Engineers International 1981-1986. (BLET, 14 Aug 2009)
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